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Personalized Cancer Medicine

NCGC runs the largest research project in Norway within cancer genomics

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The Norwegian 1000 genomes project

  A database of Norwegian normal genetic variation   As part of the NCGC studies of tumour mutations, we determine also the normal variants in blood samples from all patients. Since the detailed genetic profiles are very sensitive information, we will only...

The NCGC prostate cancer study is published in European Urology

  The study by Løvf et al, “High degree of genomic heterogeneity in multifocal primary prostate cancer” is now in press in European Urology (Journal impact factor 17,6). This detailed study by the group of Rolf I Skotheim at the OUS Institute for...

What is personalised cancer treatment?

  Personalised medicine, or precision medicine, is when we can better adapt disease treatment to the genetics of each patient and molecular subtype of the disease The recent development of high-throughput DNA sequencing hs enabled us to analyse in molecular...

NCGC participates in ICGC mutation calling benchmark study

  Published in Nature Communications   There are numerous variations to the algorithms used for detection of somatic mutations in cancer based on next generation sequencing, and these have a profound effect on what mutations are detected and which artefacts...